After half a year of development time Outertech has released a Cacheman version with Windows 10 compatibility. Version 7.x will still be maintained with bug fixes, but Cacheman 10 is the best option for all operating systems (Windows 10, 8.x, 7, Vista and XP).

Most notable changes
Core rewrite to support the Windows 10 kernel.
Several Windows 10 tweaks added.
Added support for Intel Skylake processors (Core i7-6700K,i5-6600K,etc).
New Graphics | CAD Workstation profile.
Information tab display shows process Read/Write statistics.
Improved support for DDR4 memory.
Optimized memory handling for systems with 16 GB of RAM or more.
Processes can now be marked with colors.
Tray icon will show menu now also on single click.
New skins.